The Doubletree Hotel by Hilton San Francisco South Airport Blvd offers over 7,000 sq. ft. of meeting & event space for up to 250 guests. Adjacent to the South San Francisco Convention Center, we are conveniently located right off US-101. Our hotel is less than four miles from San Francisco International Airport. Corporations like Genentech and Plenty Unlimited Inc. are within three miles. Adjacent to South San Francisco Convention Center, we are located right off US-101. The hotel is less than four miles from San Francisco International Airport. Corporations like Genentech and Plenty Unlimited Inc. are within three miles. Visit Downtown, the Golden Gate Bridge, and Bay area beaches, all within 20 miles of us.