21c Museum Hotel St. Louis

1528 Locust St, Saint Louis, MO
300 Capacity
$1,250 to $4,400 for 50 Guests
With more than 14,000 square feet of contemporary event and exhibition space surrounded by curated art, 21c St. Louis offers a distinctive setting for gatherings of every kind. Filled with natural light and equipped with modern meeting technology, our versatile venues are ideal for board retreats, executive meetings, cocktail receptions, gala dinners, charitable events, intimate weddings, and other special occasions. Your wedding day deserves a setting as memorable as the occasion itself. From rehearsal dinners and ceremonies to receptions and celebrations, 21c St. Louis provides unique, art-filled spaces designed to leave a lasting impression. Skip the traditional banquet hall and create an unforgettable experience in one of the city's most sought after event destinations.

Event Pricing

Open Bar Packages
350 people max
$29 - $62 per person
Cocktail Party
300 people max
$25 - $65 per person
Breakfast Buffet
300 people max
$28 - $48 per person
Lunch Buffet or Plated Pricing
300 people max
$40 - $60 per person
Dinner Buffet, or Plated Pricing
300 people max
$70 - $88 per person

People Often Ask

21c Museum Hotel St. Louis is located in the heart of St. Louis in the Downtown West neighborhood, just a few blocks from major attractions like City Museum, Enterprise Center, and Energizer Park. We’re conveniently located ~5-10 minutes from the downtown exits of major highways like I-64 / I-40 or I-44. Take MetroLink from Lambert Airport via the Red Line toward Shiloh–Scott, getting off at the 8th & Pine Station and walk ~15 minutes west to Locust Street.
Valet parking is available for $50 per night for 21c hotel guests, with discounts offered for event clients. Metered street parking is available on surrounding streets.
Yes! For our event clients we're happy to provide discounted pricing for our guestrooms. You'll be provided a customized link to distribute to guests to book their discounted rate.

Event Spaces

Amphitheater
Amphitheater
Amphitheatre
160 Capacity
Billiards Room
Billiards Room
General Event Space
50 Capacity
Conference Room
Conference Room
Fixed Board Room
10 Capacity
Gallery Four
Gallery Four
General Event Space
40 Capacity
Gallery One
Gallery One
Pre-Function
75 Capacity
Gallery Three
Gallery Three
General Event Space
120 Capacity
Gallery Two
Gallery Two
General Event Space
170 Capacity
Main Gallery
Main Gallery
General Event Space
325 Capacity

Additional Info

Neighborhood
Venue Types
Amenities
  • Full Bar/Lounge
  • Indoor Pool
  • On-Site Catering Service
  • Outdoor Function Area
  • Valet Parking
  • Wireless Internet/Wi-Fi
Features
  • Max Number of People for an Event: 300
  • Number of Event/Function Spaces: 8
  • Special Features: 21c provides all the essentials for a seamless and memorable event. From the moment your contract is finalized, our experienced event planning team will collaborate with you every step of the way to bring your vision to life.
  • Total Meeting Room Space (Square Feet): 14,000