The Holiday Inn Express Sioux Falls Hotel is conveniently located at Exit 406 on I-90, directly adjacent to the Interstate. Approximately 8 miles east of Sioux Falls Regional Airport in Sioux Falls, SD, or 10 miles from downtown Sioux Falls. Intersects State Hwy 11, SD. The Holiday Inn Express Hotel is a 90% non-smoking hotel and offers: free Express Start breakfast bar, free local calls, wireless internet access and Priority Club Rewards benefits. Visit Brandon, SD and stay smart at the Holiday Inn Express Hotel.